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docs: miniwdl engine docs and example project for GATK best practices (
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…#158)

* add engine docs
* add miniwdl examples
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markjschreiber authored and Elliot Smith committed Nov 16, 2021
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6 changes: 6 additions & 0 deletions examples/gatk-best-practices-project-miniwdl/README.md
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## Introduction

This project includes workflows based on [GATK Best Practices](https://gatk.broadinstitute.org/hc/en-us), developed by
the [Broad Institute](https://www.broadinstitute.org/). More information on how these workflows work is available in
the [GATK Workflows Github repository](/~https://github.com/gatk-workflows).

72 changes: 72 additions & 0 deletions examples/gatk-best-practices-project-miniwdl/agc-project.yaml
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---
name: GATK
schemaVersion: 1
workflows:
gatk4-data-processing:
type:
language: wdl
version: 1.0
sourceURL: ./gatk4-data-processing
gatk4-germline-snps-indels:
type:
language: wdl
version: 1.0
sourceURL: ./gatk4-germline-snps-indels
gatk4-basic-joint-genotyping:
type:
language: wdl
version: 1.0
sourceURL: ./gatk4-basic-joint-genotyping
seq-format-validation:
type:
language: wdl
version: 1.0
sourceURL: ./seq-format-validation
bam-to-unmapped-bams:
type:
language: wdl
version: 1.0
sourceURL: ./seq-format-conversions/bam-to-unmapped-bams
cram-to-bam:
type:
language: wdl
version: 1.0
sourceURL: ./seq-format-conversions/cram-to-bam
interleaved-fastq-to-paired-fastq:
type:
language: wdl
version: 1.0
sourceURL: ./seq-format-conversions/interleaved-fastq-to-paired-fastq
paired-fastq-to-unmapped-bam:
type:
language: wdl
version: 1.0
sourceURL: ./seq-format-conversions/paired-fastq-to-unmapped-bam
gatk4-rnaseq-germline-snps-indels:
type:
language: wdl
version: 1.0
sourceURL: ./gatk4-rnaseq-germline-snps-indels
data:
- location: s3://gatk-test-data
readOnly: true
- location: s3://broad-references
readOnly: true
- location: s3://1000genomes-dragen-3.7.6
readOnly: true
- location: s3://healthai-public-assets-us-east-1/agc-demo-data
readOnly: true
contexts:
# The on demand context uses on-demand EC2 instances which may be more expensive but will not be interrupted
onDemandCtx:
requestSpotInstances: false
engines:
- type: wdl
engine: miniwdl

# The spot context uses EC2 spot instances which are usually cheaper but may be interrupted
spotCtx:
requestSpotInstances: true
engines:
- type: wdl
engine: miniwdl
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{
"mainWorkflowURL": "gatk4-basic-joint-genotyping.wdl",
"inputFileURLs": [
"gatk4-basic-joint-genotyping.inputs.json"
],
"engineOptions": "--no-cache"
}
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{
"BasicJointGenotyping.input_gvcfs": [
"s3://1000genomes-dragen-3.7.6/data/individuals/hg38-graph-based/NA12329/NA12329.hard-filtered.gvcf.gz",
"s3://1000genomes-dragen-3.7.6/data/individuals/hg38-graph-based/NA06984/NA06984.hard-filtered.gvcf.gz",
"s3://1000genomes-dragen-3.7.6/data/individuals/hg38-graph-based/NA06989/NA06989.hard-filtered.gvcf.gz"
],
"BasicJointGenotyping.ref_fasta": "s3://broad-references/hg38/v0/Homo_sapiens_assembly38.fasta",
"BasicJointGenotyping.ref_fasta_index": "s3://broad-references/hg38/v0/Homo_sapiens_assembly38.fasta.fai",
"BasicJointGenotyping.ref_dict": "s3://broad-references/hg38/v0/Homo_sapiens_assembly38.dict",
"BasicJointGenotyping.interval_list": "s3://broad-references/hg38/v0/hg38.even.handcurated.20k.chr20_test.intervals",
"BasicJointGenotyping.callset_name": "Trio"
}
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