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Enhance Alignment Accuracy for Short Reads by Integrating map-ont and splice Options #45

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akikuno opened this issue Jul 10, 2024 · 1 comment
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bug🐛 Something isn't working request💡 New feature or request solved Done. Will close in the next release.

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@akikuno
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akikuno commented Jul 10, 2024

📋 Description

When aligning short reads of approximately 350bp, there are cases where the map-ont option better represents the actual read alignment than the sr option.

image

Therefore, while currently only processing reads below 500bp with sr, we will modify it to include alignments with map-ont (and splice), and change it to select the optimal preset using extract_best_preset.

(This is more dependent on the behavior of mappy/minimap2 rather than a bug in DAJIN2.)

💬 Current Behavior

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🎯 Expected Behavior

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⚠️ Error message

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🔍 Environment

- OS: WSL2 Ubuntu
- DAJIN2 version: 0.5.2
- Python version: 3.10

📎 Anything else?

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@akikuno akikuno added bug🐛 Something isn't working request💡 New feature or request labels Jul 10, 2024
@akikuno akikuno self-assigned this Jul 10, 2024
@akikuno akikuno added ongoing🔜 Currently in progress solved Done. Will close in the next release. and removed ongoing🔜 Currently in progress labels Jul 10, 2024
@akikuno
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akikuno commented Jul 12, 2024

Solved: 9e7fb93

@akikuno akikuno mentioned this issue Jul 16, 2024
@akikuno akikuno closed this as completed Jul 17, 2024
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