diff --git a/src/lib/generateRules.js b/src/lib/generateRules.js
index 57bb1d140cd3..05bdd784e95e 100644
--- a/src/lib/generateRules.js
+++ b/src/lib/generateRules.js
@@ -119,10 +119,20 @@ function applyImportant(matches, classCandidate) {
 
   let result = []
 
+  function isInKeyframes(rule) {
+    return rule.parent && rule.parent.type === 'atrule' && rule.parent.name === 'keyframes'
+  }
+
   for (let [meta, rule] of matches) {
     let container = postcss.root({ nodes: [rule.clone()] })
 
     container.walkRules((r) => {
+      // Declarations inside keyframes cannot be marked as important
+      // They will be ignored by the browser
+      if (isInKeyframes(r)) {
+        return
+      }
+
       let ast = selectorParser().astSync(r.selector)
 
       // Remove extraneous selectors that do not include the base candidate
diff --git a/tests/important-modifier.test.js b/tests/important-modifier.test.js
index 6d30fd0bceb3..6f6f1a8de54a 100644
--- a/tests/important-modifier.test.js
+++ b/tests/important-modifier.test.js
@@ -150,4 +150,34 @@ crosscheck(() => {
       `)
     })
   })
+
+  test('the important modifier does not break keyframes', () => {
+    let config = {
+      content: [
+        {
+          raw: html` <div class="!animate-pulse"></div> `,
+        },
+      ],
+      corePlugins: { preflight: false },
+    }
+
+    let input = css`
+      @tailwind utilities;
+    `
+
+    return run(input, config).then((result) => {
+      expect(result.css).toMatchFormattedCss(css`
+        @keyframes pulse {
+          50% {
+            opacity: 0.5;
+          }
+        }
+
+        .\!animate-pulse {
+          animation: 2s cubic-bezier(0.4, 0, 0.6, 1) infinite pulse !important;
+        }
+      `)
+    })
+  })
 })
+