diff --git a/.pre-commit-config.yaml b/.pre-commit-config.yaml
index fb66f9556..d3ee5ade9 100644
--- a/.pre-commit-config.yaml
+++ b/.pre-commit-config.yaml
@@ -12,11 +12,11 @@ repos:
   - id: end-of-file-fixer
   - id: trailing-whitespace
 - repo: /~https://github.com/asottile/pyupgrade
-  rev: v2.23.0
+  rev: v2.23.1
   hooks:
   - id: pyupgrade
 - repo: /~https://github.com/PyCQA/isort
-  rev: 5.9.2
+  rev: 5.9.3
   hooks:
   - id: isort
 - repo: /~https://github.com/psf/black
@@ -47,4 +47,4 @@ repos:
   rev: "3.9.2"
   hooks:
   - id: flake8
-    additional_dependencies: ["flake8-bugbear == 20.1.4"]
+    additional_dependencies: ["flake8-bugbear == 21.4.3"]
diff --git a/docs/changelog/2159.bugfix.rst b/docs/changelog/2159.bugfix.rst
new file mode 100644
index 000000000..92a3980d9
--- /dev/null
+++ b/docs/changelog/2159.bugfix.rst
@@ -0,0 +1 @@
+upgrade embedded pip to ``21.2.2`` from ``21.1.3`` and setuptools to ``57.4.0`` from ``57.1.0`` - by :user:`gaborbernat`
diff --git a/src/virtualenv/seed/wheels/embed/__init__.py b/src/virtualenv/seed/wheels/embed/__init__.py
index f47c962c0..a3bef6512 100644
--- a/src/virtualenv/seed/wheels/embed/__init__.py
+++ b/src/virtualenv/seed/wheels/embed/__init__.py
@@ -6,28 +6,28 @@
 BUNDLE_FOLDER = Path(__file__).absolute().parent
 BUNDLE_SUPPORT = {
     "3.10": {
-        "pip": "pip-21.1.3-py3-none-any.whl",
-        "setuptools": "setuptools-57.1.0-py3-none-any.whl",
+        "pip": "pip-21.2.2-py3-none-any.whl",
+        "setuptools": "setuptools-57.4.0-py3-none-any.whl",
         "wheel": "wheel-0.36.2-py2.py3-none-any.whl",
     },
     "3.9": {
-        "pip": "pip-21.1.3-py3-none-any.whl",
-        "setuptools": "setuptools-57.1.0-py3-none-any.whl",
+        "pip": "pip-21.2.2-py3-none-any.whl",
+        "setuptools": "setuptools-57.4.0-py3-none-any.whl",
         "wheel": "wheel-0.36.2-py2.py3-none-any.whl",
     },
     "3.8": {
-        "pip": "pip-21.1.3-py3-none-any.whl",
-        "setuptools": "setuptools-57.1.0-py3-none-any.whl",
+        "pip": "pip-21.2.2-py3-none-any.whl",
+        "setuptools": "setuptools-57.4.0-py3-none-any.whl",
         "wheel": "wheel-0.36.2-py2.py3-none-any.whl",
     },
     "3.7": {
-        "pip": "pip-21.1.3-py3-none-any.whl",
-        "setuptools": "setuptools-57.1.0-py3-none-any.whl",
+        "pip": "pip-21.2.2-py3-none-any.whl",
+        "setuptools": "setuptools-57.4.0-py3-none-any.whl",
         "wheel": "wheel-0.36.2-py2.py3-none-any.whl",
     },
     "3.6": {
-        "pip": "pip-21.1.3-py3-none-any.whl",
-        "setuptools": "setuptools-57.1.0-py3-none-any.whl",
+        "pip": "pip-21.2.2-py3-none-any.whl",
+        "setuptools": "setuptools-57.4.0-py3-none-any.whl",
         "wheel": "wheel-0.36.2-py2.py3-none-any.whl",
     },
     "3.5": {
diff --git a/src/virtualenv/seed/wheels/embed/pip-21.1.3-py3-none-any.whl b/src/virtualenv/seed/wheels/embed/pip-21.1.3-py3-none-any.whl
deleted file mode 100644
index d96a40a92..000000000
Binary files a/src/virtualenv/seed/wheels/embed/pip-21.1.3-py3-none-any.whl and /dev/null differ
diff --git a/src/virtualenv/seed/wheels/embed/pip-21.2.2-py3-none-any.whl b/src/virtualenv/seed/wheels/embed/pip-21.2.2-py3-none-any.whl
new file mode 100644
index 000000000..aea9c37a7
Binary files /dev/null and b/src/virtualenv/seed/wheels/embed/pip-21.2.2-py3-none-any.whl differ
diff --git a/src/virtualenv/seed/wheels/embed/setuptools-57.1.0-py3-none-any.whl b/src/virtualenv/seed/wheels/embed/setuptools-57.4.0-py3-none-any.whl
similarity index 90%
rename from src/virtualenv/seed/wheels/embed/setuptools-57.1.0-py3-none-any.whl
rename to src/virtualenv/seed/wheels/embed/setuptools-57.4.0-py3-none-any.whl
index 063dafc1b..af8f8ba21 100644
Binary files a/src/virtualenv/seed/wheels/embed/setuptools-57.1.0-py3-none-any.whl and b/src/virtualenv/seed/wheels/embed/setuptools-57.4.0-py3-none-any.whl differ