diff --git a/OpenEXR/config/CMakeLists.txt b/OpenEXR/config/CMakeLists.txt
index b52ad0d556..6e14e10b66 100644
--- a/OpenEXR/config/CMakeLists.txt
+++ b/OpenEXR/config/CMakeLists.txt
@@ -47,6 +47,9 @@ set(OPENEXR_IMF_HAVE_COMPLETE_IOMANIP TRUE)
 
 if(APPLE)
   set(OPENEXR_IMF_HAVE_DARWIN TRUE)
+  if (${CMAKE_OSX_ARCHITECTURES} MATCHES arm64)
+    set(OPENEXR_IMF_HAVE_GCC_INLINE_ASM_AVX FALSE)
+  endif()
 endif()
 
 configure_file(OpenEXRConfig.h.in_cmake ${CMAKE_CURRENT_BINARY_DIR}/OpenEXRConfig.h)